Sword of chaos activation code 20192/13/2023 ![]() In hamsters infected with higher doses of L. interrogans in kidney and high histopathological scores after exposure to low infection doses (∼10 3 bacteria). In contrast to the females, male hamsters had high burdens of L. We found that male hamsters were considerably more susceptible to leptospirosis, given that only 6.3% survived infection, whereas 68.7% of the females survived the same infection doses. ![]() In this study, we used an acute animal model of disease to analyze leptospirosis in male and female hamsters infected side by side with low but increasing doses of Leptospira interrogans serovar Copenhageni. ![]() A somewhat contradictory published body of evidence suggests that sex impacts severity outcomes of human leptospirosis. ![]()
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